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Administration of l-lactate elevated l-lactylation levels and suppressed the pro-inflammatory phenotype of microglia, thus improving locomotor recovery ( 80 )

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Recently, peptides that target next-generation immune checkpoints, such as T-cell immunoglobulin-3 (TIM-3), lymphocyte activation gene 3 (LAG-3), and T-cell immunoreceptor with Ig and ITIM domains (TIGIT), have attracted increasing attention